Effects of human milk oligosaccharides and early introduction of dietary sugars on development of the infant gut microbiome, cognitive outcomes, eating behaviors and obesity

Longitudinal cohort study in 200 Latino newborns who have been followed since birth with detailed measures of nutrition, body composition, environmental exposures and repeated sampling of gut microbiome and breastmilk.

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Funding

RO1 from NIDDK:

More details on this funding at NIH Reporter:
Impact of Early feeding and human milk oligosaccharides on obesity and brain development → 

Project 1 Funding from our P50 Center:

More details on this funding at NIH Reporter:
Early Life Social, Environmental, and Nutritional Determinants of Disease → 

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Key Publications

Human Milk Oligosaccharide 2’-fucosyllactose Links Feedings at 1 month to Cognitive Development at 24 months in Infants of Normal and Overweight Mothers

Associations of Maternal Fructose and Sugar-Sweetened Beverage and Juice Intake During Lactation With Infant Neurodevelopmental Outcomes at 24 Months

Changes in Individual Human Milk Oligosaccharide (HMO) Concentrations Over the Course of Lactation in a Prospective Cohort of Hispanic Mother-Infant Pairs

Prenatal Exposure to Ambient Air Pollutants and Early Infant Growth and Adiposity in the Southern California Mother’s Milk Study 

Early Life Gut Microbiota is Associated with Rapid Infant Growth in Hispanics from Southern California 

Associations of Human Milk Oligosaccharides with Infant Brain Tissue Organization and Regional Blood Flow at 1 Month of Age

Associations Between Dietary Sugar and Fiber on Infant Gut Microbiome Colonization at 6 Months of Age

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